Video stuttering & no sound

What happend?
If I start an *.mkv file from my NAS the movie starts stuttering and sound is muted.
This behaviour does not stop at any time.

Media Info
http://paste.osmc.io/eficogeweq.tex

Log
I switched debug on and restarted the Pi 3 and reproduces the problem. The problem starts at ~15:03:49 until the end of the log
http://paste.osmc.io/lofabudume.coffee

CPU is at 100%

edit:
I guess the interesting path is this:

Code:
15:04:50 285.137512 T:1487922160 NOTICE: CDVDPlayerAudio::OutputPacket skipping a packets of duration 32
15:04:50 285.169586 T:1956283312 NOTICE: Previous line repeats 7 times.

I used Notepad++ to count the occurences of “OutputPacket skipping a packets” and the result was 4457.